CIC biomaGUNE has a radiochemistry laboratory equipped with 5 shielded hot cells housing versatile automatic synthesis, suitable for the production (synthesis, purification and quality control) of PET and SPECT radiotracers. The facility has specially designed modules for:
- Synthesis of [11C] CH3I / [11C] CH3OTf from [11C] CO2 / [11C] CH4, and subsequent methylation reaction
- 18F-fluorination by nucleophilic and electrophilic substitution
- Radiotracer synthesis using microfluidics technology
- Chelation reactions using radiometals (68Ga, 67Ga, 64Cu, 89Zr, etc)
In addition, the laboratory has two shielded hot cells for manual handling of radioactive substances, suitable for the preparation of mono-doses or to perform syntheses with small amounts of radioactivity.
The quality control lab, sited into the production lab, is equipped with state of art equipment to perform the complete quality control of the synthesized radiotracers, including the following equipment.
Additionally, CNIC has a radiochemistry/nanochemistry lab which includes a relaxometer of 1.5 Tesla, nanosizer ZS-90, homogenizer, 68Ga generator and a synthesis module equipped with an organic chemistry lab.